1 post tagged “human and animal health”

Friday, May 9, 2008 USDA VS KOREA typical or atypical BSe

 

Honorable people of Korea

a kind and warm greetings from Texas.

i cannot sit here and allow my government to lie to the korean people. i have been following the issue of Transmissible Spongiform Encephalopathy for over a decade, since the death of my mother to the Heidenhain Variant of Creutzfeldt Jakob Disease, confirmed. i have followed this on a daily basis since 12-14-97. there is so much i want to tell you, that the USDA and the FDA are not telling you.

i almost got to see your beautiful country, but in the last minute, my trip was cancelled. i was asked to come speak a year or so ago ;

Name: Terry S. Singeltary Sr. Date: Jan 26, 2007 Dear Terry S. Singeltary Sr. My name in Seoungwon Lee and I work for National Assemblywoman (MP) Sang-Jeong Sim, in South Korea. Below is a message from Mr. Kwon. Please get back to us regarding the letter. Thank you. Seoungwon Lee Legislative Assistant National Assembly Republic of Korea

Dear Terry S. Singeltary Sr.

Greetings from Korea.

I have learned about what you and your family have been through a internet. Being the father of a small family, I can only imagine the sense of loss that you and your family still must feel regarding your mother.

Through the internet, many people here in Korea have learnt about the story of your family and it has created a great deal of concern. Your experience had particular relevance for the citizens here, for the Korean government, in connection to the free trade agreement it is negotiating with the United States, is about to restart the sale of the unsafe American beef to the general public.

The Korean government has already imported the first load American beef and is currently going through the inspection period. There has been a great deal of controversy regarding the safety of these products, and a precipitous increase in public interest regarding the causes and symptoms of vCJD.

It is in this context that we are preparing a session together with National Assembly members and relevant NGOs to hear from those who have had direct experience with the human variant of BSE. We are very interested in hearing about the symptoms that your mother showed, your views on the response from the US government to the many deaths that resulted from this disease, the reaction from the general public, and any other area that you would wish to speak about. There would also be experts and academics in the area to speak at the session as well. We believe that it would greatly contribute to raising awareness about the issue, as well as help politicians and civic activists to consider the repercussions of the beef import issue.

We would like to request your help in this regard. We are planning for the session to be held in Seoul on the 23rd of this November. We would very much like to have you present in order to help prevent such tragic incidents from happening in Korea. We would, of course, pay for the trip and accommodations for the duration of your stay. If you were to participate, we could also meet with members from the agricultural committee of the National Assembly and from other related organizations to urge more interest to the issue.

Please do not hesitate to offer suggestions or ask us any questions that you might have. We look forward to a positive response and to meeting you in Seoul.

Thank you. Sincerely, Sim Sang-Jeong Head of the Democratic Labor Party Parliamentary Committee on the Korea-US FTA Member of the National Assembly Republic of Korea

http://www.fpif.org/fpiftxt/3940

Please remember, the last two mad cows documented in the USA i.e. Alabama and Texas, both were of the 'atypical' BSE strain, and immediately after that, the USDA shut down the testing from 470,000 to 40,000 in the U.S. in 2007 out of about 35 million cattle slaughtered. also, science is showing that some of these atypical cases are more virulent to humans than the typical UK BSE strain ;

***Atypical forms of BSE have emerged which, although rare, appear to be more virulent than the classical BSE that causes vCJD.***

Progress Report from the National Prion Disease Pathology Surveillance Center

An Update from Stephen M. Sergay, MB, BCh & Pierluigi Gambetti, MD

April 3, 2008

http://www.aan.com/news/?event=read&article_id=4397&page=72.45.45

NEXT QUESTION, _if_ BSE is not in the USA (just not documented for many different reasons), and only atypical BSE is in the USA (plus CWD, plus, many strains of Scrapie, and Now the Nor-98 documented in 5 different states, plus TME, then why would human mad cow in the USA look like the UK nvCJD from UK BSE cows ? it was shown long ago in studies at Mission Texas that experimental transmission of USA Scrapie to USA Bovine, DID NOT LOOK LIKE UK BSE. so again, in short, why would human mad cow in the USA look like human mad cow in the UK i.e. the (nvCJD). however, i believe that BSE has been in the USA untested and undocumented for years. why on earth then does the USDA refuse to allow creekstone or anyone else test their product? simple, if you don't look/test, you don't find (see my USA VS CANADA mad cow testing blog in my reference links below) ;

There is a growing number of human CJD cases, and they were presented last week in San Francisco by Luigi Gambatti(?) from his CJD surveillance collection.

He estimates that it may be up to 14 or 15 persons which display selectively SPRPSC and practically no detected RPRPSC proteins.

http://www.fda.gov/ohrms/dockets/ac/06/transcripts/1006-4240t1.htm

http://www.fda.gov/ohrms/dockets/ac/06/transcripts/2006-4240t1.pdf

Sunday, April 20, 2008 Progress Report from the National Prion Disease Pathology Surveillance Center April 3, 2008

Atypical forms of BSE have emerged which, although rare, appear to be more virulent than the classical BSE that causes vCJD.

see full text ;

http://prionunitusaupdate2008.blogspot.com/2008/04/progress-report-from-national-prion.html

MAD COW DISEASE terminology UK c-BSE (typical), atypical BSE H or L, and or Italian L-BASE

http://bse-atypical.blogspot.com/2008/03/mad-cow-disease-terminology-uk-c-bse.html

CJD TEXAS (cjd clusters)

http://cjdtexas.blogspot.com/

Honorable people of Korea, young and old, rich and poor, I wish to send this data to you, I hope you dont mind, and please spread the truth. the fda ruminant-to-ruminant feed ban has failed terribly since the inception on 8-4-97. it was nothing but ink on paper. however, the usda fda et al does not tell the honorable people of Korea this. The feed ban is one of those firewalls the FDA et al like to boast about all the time. In 2007, in one weekly enforcement report, the fda recalled 10,000,000+ pounds of BANNED MAD COW FEED, 'in commerce', and i can tell you that most of it was fed out ;

10,000,000+ LBS. of PROHIBITED BANNED MAD COW FEED I.E. MBM IN COMMERCE USA 2007

Date: March 21, 2007 at 2:27 pm PST REASON Blood meal used to make cattle feed was recalled because it was cross-contaminated with prohibited bovine meat and bone meal that had been manufactured on common equipment and labeling did not bear cautionary BSE statement. VOLUME OF PRODUCT IN COMMERCE 42,090 lbs. DISTRIBUTION WI

REASON Products manufactured from bulk feed containing blood meal that was cross contaminated with prohibited meat and bone meal and the labeling did not bear cautionary BSE statement. VOLUME OF PRODUCT IN COMMERCE 9,997,976 lbs. DISTRIBUTION ID and NV

END OF ENFORCEMENT REPORT FOR MARCH 21, 2007

http://www.fda.gov/bbs/topics/enforce/2007/ENF00996.html

Subject: MAD COW FEED RECALL USA SEPT 6, 2006 1961.72 TONS IN COMMERCE AL, TN, AND WV Date: September 6, 2006 at 7:58 am PST

snip... see listings and references of enormous amounts of banned mad cow protein 'in commerce' in 2006 and 2005 ;

see full text ;

Friday, April 25, 2008

Substances Prohibited From Use in Animal Food or Feed [Docket No. 2002N-0273] (Formerly Docket No. 02N-0273) RIN 0910-AF46

http://madcowfeed.blogspot.com/2008/04/substances-prohibited-from-use-in.html

2006 was a banner year too for mad cow protein fed out into commerce. those were just one of many ;

Specified Risk Materials

http://madcowspontaneousnot.blogspot.com/2008/02/specified-risk-materials-srm.html

Tuesday, April 29, 2008

Interference at the EPA - Science and Politics at the U.S. Environmental Protection Agency

please see full text ;

http://sciencebushwhacked.blogspot.com/

CJD QUESTIONNAIRE

http://cjdquestionnaire.blogspot.com/

DOWNER COW SCHOOL LUNCH PROGRAM

http://downercattle.blogspot.com/

http://downercattle.blogspot.com/2008/04/gao-report-on-humane-methods-of.html

http://downercattle.blogspot.com/2008/03/usda-certified-dead-stock-downer-cow.html

http://downercattle.blogspot.com/2008/03/usda-still-pandering-to-industry-still_27.html

http://downercattle.blogspot.com/2008/03/usda-still-pandering-to-industry-still.html

http://downercattle.blogspot.com/2008/03/recalled-beef-from-chino-slaughterhouse.html

http://downercattle.blogspot.com/2008/03/mad-cow-disease-typical-vs-atypical.html

http://downercattle.blogspot.com/2008/03/downer-cow-blues-senators-want.html

http://downercattle.blogspot.com/2008/03/mr-will-hueston-dvm-on-school-lunch.html

http://downercattle.blogspot.com/2008/03/california-downer-cow-meat-worker-i-was.html

http://downercattle.blogspot.com/2008/03/usda-questions-and-answers.html

http://downercattle.blogspot.com/2008/03/usda-to-hallmark-we-want-our-plaque.html

http://downercattle.blogspot.com/2008/03/house-committee-subpoenas.html

http://downercattle.blogspot.com/2008/03/california-lists-possible-recipients-of.html

http://downercattle.blogspot.com/2008/03/to-hard-working-employees-of-usda-and.html

http://downercattle.blogspot.com/2008/02/beef-recall-nationwide-school-lunch.html

http://downercattle.blogspot.com/2008/02/transcript-technical-briefing.html

Thursday, May 1, 2008

DEAD STOCK DOWNER COW BAN i.e. non-ambulatory policy still not changed by USDA May 1, 2008

http://downercattle.blogspot.com/2008/05/dead-stock-downer-cow-ban-ie-non.html

[Docket No. 03-025IFA] FSIS Prohibition of the Use of Specified Risk Materials for Human Food and Requirement for the Disposition of Non-Ambulatory Disabled Cattle

03-025IFA 03-025IFA-2 Terry S. Singeltary

9/13/2005

http://www.fsis.usda.gov/OPPDE/Comments/03-025IFA/03-025IFA-2.pdf

[Docket No. FSIS-2006-0011] FSIS Harvard Risk Assessment of Bovine Spongiform Encephalopathy (BSE)

http://www.fsis.usda.gov/OPPDE/Comments/2006-0011/2006-0011-1.pdf

NOR-98 ATYPICAL SCRAPIE USA UPDATE AS AT OCT 2007

http://nor-98.blogspot.com/

SCRAPIE USA

http://scrapie-usa.blogspot.com/

Saturday, April 12, 2008

Evidence of scrapie transmission via milk

http://scrapie-usa.blogspot.com/2008/04/evidence-of-scrapie-transmission-via.html

CHRONIC WASTING DISEASE

http://chronic-wasting-disease.blogspot.com/

Thursday, April 03, 2008

A prion disease of cervids: Chronic wasting disease 2008

http://chronic-wasting-disease.blogspot.com/2008/04/prion-disease-of-cervids-chronic.html

Transmissible Mink Encephalopathy TME

http://transmissible-mink-encephalopathy.blogspot.com/

MAD COW TESTING USDA AND CANADA

http://madcowtesting.blogspot.com/

http://madcowtesting.blogspot.com/2008/04/mbm-greaves-meat-offal-live-cattle.html

http://madcowtesting.blogspot.com/2008/04/report-on-investigation-of-eleventh.html

http://madcowtesting.blogspot.com/2008/03/rapid-typing-of-transmissible.html

http://madcowtesting.blogspot.com/2008/01/docket-no-aphis-2006-0026-rin-0579-ac45.html

http://madcowtesting.blogspot.com/2008/01/bse-oie-usda.html

http://madcowtesting.blogspot.com/2007/12/bse-case-confirmed-in-alberta-december.html

http://madcowtesting.blogspot.com/2007/10/bse-base-mad-cow-testing-texas-usa-and.html

Friday, March 21, 2008 Association between Deposition of Beta-Amyloid and Pathological Prion Protein in Sporadic Creutzfeldt-Jakob Disease Original Paper

http://betaamyloidcjd.blogspot.com/2008/03/association-between-deposition-of-beta.html

10 Million Baby Boomers to have Alzheimer's in the coming decades 2008 Alzheimer's disease facts and figures

Alzheimer's and CJD

http://betaamyloidcjd.blogspot.com/

Monday, May 5, 2008

STATEMENT OF DR. RICHARD RAYMOND USDA UNDERSECRETARY FOR FOOD SAFETY Regarding the Safety of the U.S. Food Supply

please see full text with some additional information the good Dr. Raymond seems to have forgotten about ;

http://usdameatexport.blogspot.com/2008/05/statement-of-dr-richard-raymond-usda.html

Friday, April 18, 2008

Statement by Agriculture Secretary Ed Schafer on South Korea Reopening Market to U.S. Beef and Beef Products in Line with International Standards

http://usdameatexport.blogspot.com/2008/04/statement-by-agriculture-secretary-ed.html

Thursday, November 1, 2007 Transcript of Questions and Answers: Acting Agriculture Secretary Chuck Conner with Media After U.S. Meat Export Federation Remarks

TRANSCRIPT

Release No. 0317.07 Contact: Office of Communications (202)720-4623

http://usdameatexport.blogspot.com/2007/11/transcript-of-questions-and-answers.html

P.S. DO NOT, forget about friendly fire iCJD. it's not just about 'consumption'. the medical, surgical, and dental arena will play a huge role in these long term death sentences from animal TSE via secondary transmission i.e. 'friendly fire', and with the atypical BSE being more virulent, it's anyone's guess how this will play out in the long run. you here different groups that don't believe, you here the old 'your more likely to get hit by a car than die from CJD'. well, maybe so, but my mother and many more did not die from getting hit by a car, they died from CJD, my mothers being the hvCJD (documented). ...TSS

iatrogenic Creutzfeldt Jakob Disease

Reports of incidents of potential iatrogenic exposure to CJD via surgery: 01 January 2000 to 31 Dec 2007

There were a total of 329 incidents reported during this period (table 1). Eleven surgical incidents were reported between 1 July and 31 December 2007 (since the previous update report). A surgical incident occurs when a patient undergoes surgery but is only identified as having CJD or being at risk of CJD at a later date. This means that the Advisory Committee on Dangerous Pathogens (ACDP) transmissible spongiform encephalopathy working group infection control guidelines would not have been followed. The surgery carried out on an index patient with, or at risk of, CJD may result in contamination of the instruments with abnormal prion protein. Table 1 shows the number of CJD surgical incidents reported to the CJD Incidents Panel from January 2000 to December 2007 by the diagnosis of the index patient.

Table 1 CJD Surgical Incidents (n=329) reported to the CJD Incidents Panel, by diagnosis of index patient: January 2000 to Dec 2007

snip... see full text ;

http://www.hpa.org.uk/hpr/infections/ei_cjd.htm#cjd

Wednesday, January 02, 2008 Risk factors for sporadic Creutzfeldt-Jakob disease Wednesday, January 02, 2008 Risk factors for sporadic Creutzfeldt-Jakob disease

FURTHER INTO THIS STUDY ;

http://creutzfeldt-jakob-disease.blogspot.com/2008/01/risk-factors-for-sporadic-creutzfeldt.html

http://creutzfeldt-jakob-disease.blogspot.com/2007/12/risk-factors-for-sporadic-creutzfeldt.html

Monday, December 31, 2007 Risk Assessment of Transmission of Sporadic Creutzfeldt-Jakob Disease in Endodontic Practice in Absence of Adequate Prion Inactivation

http://creutzfeldt-jakob-disease.blogspot.com/2007/12/risk-assessment-of-transmission-of.html

IN short, you might want to communicate these factors of iCJD to your fellow Koreans in the USA who are having medical, surgical and or dental work done. With the many different animal TSEs in the USA of typical and atypical phenotype, the consumption thereof of these TSE infected animals, and the following medical, surgical, and or dental work done on any individual consuming such tainted product, the fact that Koreans are more susceptible to contracting a TSE, one must ponder all these factors ;

Polymorphisms of the prion protein gene (PRNP) in a Korean population Journal Journal of Human Genetics Publisher Springer Japan ISSN 1434-5161 (Print) 1435-232X (Online) Issue Volume 49, Number 6 / June, 2004 Category Short Communication DOI 10.1007/s10038-004-0150-7 Pages 319-324 Subject Collection Biomedical and Life Sciences SpringerLink Date Monday, May 17, 2004

Byung-Hoon Jeong1, Jae-Hwan Nam2, Yun-Jung Lee1, Kyung-Hee Lee1, Myoung-Kuk Jang1, Richard I. Carp3, Ho-Dong Lee2, Young-Ran Ju2, Sangmee Ahn Jo2, Keun-Yong Park2 and Yong-Sun Kim1, 4

(1) Ilsong Institute of Life Science, Hallym University, Ilsong Building, 1605-4, Gwanyang-dong, Dongan-gu, Anyang, Kyounggi-do, 431-060, South Korea (2) Department of Virology, Korea National Institute of Health, Eunpyung-gu, Seoul, 122-701, South Korea (3) New York State Institute for Basic Research in Developmental Disabilities, Staten Island, NY 10314, USA (4) Department of Microbiology, College of Medicine, Hallym University, 1605-4, Gwanyang-dong, Dongan-gu, Anyang, Kyounggi-do, 431-060, South Korea

Received: 7 January 2004 Accepted: 5 March 2004 Published online: 18 May 2004

Abstract Human prion protein gene (PRNP) has been considered to be involved in the susceptibility of humans to prion diseases. Polymorphisms of methionine (Met)/valine (Val) at codon 129 and of glutamic acid (Glu)/lysine (Lys) at codon 219 are thought to play an important role in susceptibility to sporadic, iatrogenic and variant Creutzfeldt–Jakob disease (CJD). Although the genotype distribution of polymorphisms in PRNP open reading frame (ORF) has been reported in many European populations, among Asian groups, it has been reported only in the Japanese population. We examined the PRNP polymorphisms in 529 healthy Koreans. We observed that genotype frequencies at codon 129 was 94.33% Met/Met, 5.48% Met/Val, and 0.19% Val/Val with an allele frequency of 0.971:0.029 Met:Val, and that genotype frequencies at codon 219 was 92.06% Glu/Glu, 7.94% Glu/Lys, and 0% Lys/Lys with an allele frequency of 0.96:0.04 Glu:Lys. The frequencies of the Glu/Glu genotype (2=10.075, P=0.0015) and of the Glu allele (2=9.486, P=0.0021) at codon 219 were significantly higher in the Korean population than the Japanese population. In addition, the genotype frequency of heterozygotes (12.7%) at codons 129 or/and 219 was significantly lower in Koreans than in people from Great Britain (2=89.52, P<0.0001). The deletion rate of one octarepeat (R2 deletion) was 0.38%, with 99.62% undeleted homozygotes and 0% deleted homozygote. To our knowledge, the R2 octarepeat deletion has never been found in people from countries other than Korea. The data of PRNP polymorphism at codon 219 suggest that Koreans may be more sensitive to sporadic CJD than the Japanese population. Keywords Prion protein gene - Polymorphism - Creutzfeldt–Jakob disease - Single nucleotide polymorphism - Deletion - Korean

http://www.springerlink.com/content/51h1j81h80hjrdtf/

European Journal of Human Genetics (2005) 13, 1094–1097. doi:10.1038/sj.ejhg.5201460; published online 29 June 2005

Polymorphism at 3' UTR +28 of the prion-like protein gene is associated with sporadic Creutzfeldt–Jakob disease Byung-Hoon Jeong1, Nam-Ho Kim1, Eun-Kyoung Choi1, Chaeyoung Lee1, Young-Han Song1, Jae-Il Kim2, Richard I Carp2 and Yong-Sun Kim1,3

1Ilsong Institute of Life Science, Hallym University, 1605-4 Gwanyang-dong

snip...

Our results are the first genetic association study of the PRND noncoding region with sporadic CJD. Recently, we reported that the distributions of codons 129 and 219 genotypes of PRNP in a Korean population differ significantly from those reported for other ethnic groups.24 Thus, further investigations in different ethnic groups including Europeans will be necessary to assess association between sporadic CJD and the PRND 3' UTR +28 polymorphism. Furthermore, since it is unknown whether this polymorphism affects mRNA stability or gene expression of PRND, further experiments should be conducted to clarify the role of this polymorphism in PRND function.

http://www.nature.com/ejhg/journal/v13/n9/full/5201460a.html

 

Thank You,

with kindest regards,

I am sincerely,

Terry S. Singeltary Sr.

P.O. Box 42

Bacliff, Texas USA 77518 flounder9@verizon.net

 

http://disc.yourwebapps.com/Indices/236650.html